The serotonin-1A receptor serves as a hub to regulate the activity and actions of the serotonin system, and is expressed both as a presynaptic autoreceptor on raphe neurons, and as a major postsynaptic receptor in hippocampal, cortical, and hypothalamic regions involved in mood, emotion and stress response.
URL: http://www.topix.com/health/depression/2012/09/transcriptional-regulation-at-a-htr1a-polymorphism-associated-with-mental-illness?fromrss=1
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